There is a quote by Theodosius Dobzhansky that goes: “Nothing in biology makes sense except in the light of evolution.” In response, I wish to… Read More »Who Moved My Genes? Analyzing Chromosomal Rearrangements in the LTEE
We recently published an open access video protocol in the Journal of Visualized Experiments (JoVE) covering some of the core procedures we use in the… Read More »By JoVE, we’ve done it!
We just discovered and dealt with our first major hiccups in continuing to propagate the LTEE at UT Austin. We mistakenly swapped two of the… Read More »77,000 Generation Update: Population Switcheroo and Acinetobacter Interloper
When I give talks about the long-term evolution experiment (LTEE) with E. coli,I usually focus on the results of our work, with only a quick… Read More »Revisiting the Design of the LTEE
We’re now through the first 150 days of continuing the LTEE at UT Austin. I want to take this opportunity to introduce and thank the… Read More »The First Thousand Generations at UT
Today we revived frozen samples of the 12 LTEE populations in the Barrick lab at the University of Texas at Austin to continue the Long-Term… Read More »LTEE Kickoff at UT Austin
Richard Lenski and Jeffrey Barrick spoke to Ewen Callaway about the history of the Long-Term Evolution Experiment and its move from MSU to UT Austin.… Read More »Nature News Q&A on the LTEE Handoff
I’m excited to announce two new papers posted on the bioRxiv preprint website. Both studies examine the evolution of the distribution of fitness effects (DFE)… Read More »The Changing Distribution of Fitness Effects
Today is the 34th birthday of the LTEE, which I started on February 24, 1988. With the invasion of Ukraine, however, it’s not a day… Read More »In Other News
We had a lot of snow here, but that didn’t stop Dr. Zachary Blount from making the daily LTEE transfers. You can follow Zack’s excellent… Read More »Neither Snow nor Rain nor Heat nor Gloom of Night
Greetings on this winter solstice, and welcome to this new LTEE website! The winter solstice marks a sort of new beginning, as the days become… Read More »New Beginnings
In a new paper just published in Cell Systems, Daniel Deathrage and Jeff Barrick detail an exciting approach to inferring adaptive dynamics at resolutions previously… Read More »Creative Sequencing Tool Allows Peek into Low-Frequency Mutational Dynamics
The best part of the LTEE is the wonderful people who’ve worked on it over the years including graduate and undergraduate students, postdocs, technicians, and… Read More »Nkrumah Grant and Kyle Card are in the Hood
The LTEE has inspired other teams to perform long-term evolution experiments. In this article, Michael Gresko explains a multi-year experiment performed by Ozan Bozdag, Will… Read More »National Geographic: Evolving Globs of Yeast May Unlock Mysteries of Multicellular Life
The LTEE is mentioned as background for understanding how microbes evolve in this article by Dhruv Khullar. In 1988, Richard Lenski, a thirty-one-year-old biologist at… Read More »New Yorker: How Will the Coronavirus Evolve?
The LTEE is covered in an episode of Veritasium. Check out the video below! Link: https://www.youtube.com/watch?v=w4sLAQvEH-M&t=1s