Revisiting the Design of the LTEE
When I give talks about the long-term evolution experiment (LTEE) with E. coli,I usually focus on the results of our work, with only a quick… Read More »Revisiting the Design of the LTEE
The First Thousand Generations at UT
We’re now through the first 150 days of continuing the LTEE at UT Austin. I want to take this opportunity to introduce and thank the… Read More »The First Thousand Generations at UT
LTEE Kickoff at UT Austin
Today we revived frozen samples of the 12 LTEE populations in the Barrick lab at the University of Texas at Austin to continue the Long-Term… Read More »LTEE Kickoff at UT Austin
Nature News Q&A on the LTEE Handoff
Richard Lenski and Jeffrey Barrick spoke to Ewen Callaway about the history of the Long-Term Evolution Experiment and its move from MSU to UT Austin.… Read More »Nature News Q&A on the LTEE Handoff
The Changing Distribution of Fitness Effects
I’m excited to announce two new papers posted on the bioRxiv preprint website. Both studies examine the evolution of the distribution of fitness effects (DFE)… Read More »The Changing Distribution of Fitness Effects
In Other News
Today is the 34th birthday of the LTEE, which I started on February 24, 1988. With the invasion of Ukraine, however, it’s not a day… Read More »In Other News
Neither Snow nor Rain nor Heat nor Gloom of Night
We had a lot of snow here, but that didn’t stop Dr. Zachary Blount from making the daily LTEE transfers. You can follow Zack’s excellent… Read More »Neither Snow nor Rain nor Heat nor Gloom of Night
New Beginnings
Greetings on this winter solstice, and welcome to this new LTEE website! The winter solstice marks a sort of new beginning, as the days become… Read More »New Beginnings
Creative Sequencing Tool Allows Peek into Low-Frequency Mutational Dynamics
In a new paper just published in Cell Systems, Daniel Deathrage and Jeff Barrick detail an exciting approach to inferring adaptive dynamics at resolutions previously… Read More »Creative Sequencing Tool Allows Peek into Low-Frequency Mutational Dynamics
Nkrumah Grant and Kyle Card are in the Hood
The best part of the LTEE is the wonderful people who’ve worked on it over the years including graduate and undergraduate students, postdocs, technicians, and… Read More »Nkrumah Grant and Kyle Card are in the Hood
National Geographic: Evolving Globs of Yeast May Unlock Mysteries of Multicellular Life
The LTEE has inspired other teams to perform long-term evolution experiments. In this article, Michael Gresko explains a multi-year experiment performed by Ozan Bozdag, Will… Read More »National Geographic: Evolving Globs of Yeast May Unlock Mysteries of Multicellular Life
New Yorker: How Will the Coronavirus Evolve?
The LTEE is mentioned as background for understanding how microbes evolve in this article by Dhruv Khullar. In 1988, Richard Lenski, a thirty-one-year-old biologist at… Read More »New Yorker: How Will the Coronavirus Evolve?
Veritasium: The Longest-Running Evolution Experiment
The LTEE is covered in an episode of Veritasium. Check out the video below! Link: https://www.youtube.com/watch?v=w4sLAQvEH-M&t=1s
Neerja Hajela Retires as All-Time LTEE Champion
Neerja Hajela has worked on the LTEE for over 22 years as a technician and lab manager. But alas, she is now retiring. Neerja has… Read More »Neerja Hajela Retires as All-Time LTEE Champion
BEACON Celebrates Lenski’s 60th Birthday
Many past and present LTEE researchers gathered at Michigan State University to celebrate Richard Lenski’s 60th birthday in conjunction with the annual Congress of the… Read More »BEACON Celebrates Lenski’s 60th Birthday
Through the Wormhole, with Morgan Freeman
Tony Lund was the writer and director for “Through the Wormhole” when he and his team came to MSU to tell the story of the… Read More »Through the Wormhole, with Morgan Freeman