Ara+3: The Red Scare
[Note: LTEE veterans, feel free to skip the first paragraph, but take note of the mutation in red—the ‘Chekhov’s mutation’ of this little narrative, as… Read More »Ara+3: The Red Scare
80,000 Generations: New Olympic Record
On August 7th, we froze down the 80,000-generation* populations of the LTEE. We’re pretty sure this is both a new Olympic Record and World Record… Read More »80,000 Generations: New Olympic Record
LTEE Eclipsed
Austin was in the path of totality for the Great North American Eclipse. The weather was cloudy, unfortunately, but the crescent sun peeked through enough… Read More »LTEE Eclipsed
Darwin Day 2024 in Tyler, TX
Earlier this spring, I had a fantastic visit to Tyler Junior College (TJC) and UT Tyler to give two public presentations as part of their… Read More »Darwin Day 2024 in Tyler, TX
Time to Reflect on Darwin’s Birthday
Charles Darwin, founder of our field, and the one who made biology a real science, was born on this day in 1809, an exact birthday… Read More »Time to Reflect on Darwin’s Birthday
An Update to the Changing Distribution of Fitness Effects
About a year and a half ago, I wrote about a pair of papers posted on the bioRxiv preprint website. Both papers examined the evolution… Read More »An Update to the Changing Distribution of Fitness Effects
LTEE on Big Picture Science
I recently had a great time discussing the long-term evolution experiment and more with Molly Bentley in an interview for an episode of the podcast… Read More »LTEE on Big Picture Science
Who Moved My Genes? Analyzing Chromosomal Rearrangements in the LTEE
There is a quote by Theodosius Dobzhansky that goes: “Nothing in biology makes sense except in the light of evolution.” In response, I wish to… Read More »Who Moved My Genes? Analyzing Chromosomal Rearrangements in the LTEE
By JoVE, we’ve done it!
We recently published an open access video protocol in the Journal of Visualized Experiments (JoVE) covering some of the core procedures we use in the… Read More »By JoVE, we’ve done it!
77,000 Generation Update: Population Switcheroo and Acinetobacter Interloper
We just discovered and dealt with our first major hiccups in continuing to propagate the LTEE at UT Austin. We mistakenly swapped two of the… Read More »77,000 Generation Update: Population Switcheroo and Acinetobacter Interloper
Revisiting the Design of the LTEE
When I give talks about the long-term evolution experiment (LTEE) with E. coli,I usually focus on the results of our work, with only a quick… Read More »Revisiting the Design of the LTEE
The First Thousand Generations at UT
We’re now through the first 150 days of continuing the LTEE at UT Austin. I want to take this opportunity to introduce and thank the… Read More »The First Thousand Generations at UT
LTEE Kickoff at UT Austin
Today we revived frozen samples of the 12 LTEE populations in the Barrick lab at the University of Texas at Austin to continue the Long-Term… Read More »LTEE Kickoff at UT Austin
Nature News Q&A on the LTEE Handoff
Richard Lenski and Jeffrey Barrick spoke to Ewen Callaway about the history of the Long-Term Evolution Experiment and its move from MSU to UT Austin.… Read More »Nature News Q&A on the LTEE Handoff
The Changing Distribution of Fitness Effects
I’m excited to announce two new papers posted on the bioRxiv preprint website. Both studies examine the evolution of the distribution of fitness effects (DFE)… Read More »The Changing Distribution of Fitness Effects
In Other News
Today is the 34th birthday of the LTEE, which I started on February 24, 1988. With the invasion of Ukraine, however, it’s not a day… Read More »In Other News