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2021

Consuegra J; Gaffé J; Lenski R E; Hindré T; Barrick J E; Tenaillon O; Schneider D

Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria Journal Article

Nature Communications, 12 (1), pp. 980, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Mutation Rates

Gifford I; Dasgupta A; Barrick J E

Rates of gene conversions between Escherichia coli ribosomal operons Journal Article

G3: Genes, Genomes, Genetics, 11 (2), 2021, ISSN: 21601836.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments, Mutation Rates

2020

Maddamsetti R; Grant N A

Divergent Evolution of Mutation Rates and Biases in the Long-Term Evolution Experiment with Escherichia coli Journal Article

Genome Biology and Evolution, 12 (9), pp. 1591-1603, 2020, ISSN: 1759-6653.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates

2017

Good B H; McDonald M J; Barrick J E; Lenski R E; Desai M M

The dynamics of molecular evolution over 60,000 generations Journal Article

Nature, 551 (7678), pp. 45–50, 2017, ISSN: 14764687.

Abstract | Links | BibTeX | Altmetric | Tags: Demography and Ecology, Genome Evolution, Historical Contingency, Mutation Rates, Parallelism and Divergence

The dynamics of molecular evolution over 60,000 generations

Maddamsetti R; Hatcher P J; Green A G; Williams B L; Marks D S; Lenski R E

Core genes evolve rapidly in the long-term evolution experiment with Escherichia coli Journal Article

Genome Biology and Evolution, 9 (4), pp. 1072–1083, 2017, ISSN: 17596653.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Genotypes and Phenotypes, Mutation Rates

Core genes evolve rapidly in the long-term evolution experiment with Escherichia coli

2016

Tenaillon O; Barrick J E; Ribeck N; Deatherage D E; Blanchard J L; Dasgupta A; Wu G C; Wielgoss S; Cruveiller S; Medigue C; Schneider D; Lenski R E

Tempo and mode of genome evolution in a 50,000-generation experiment. Journal Article

Nature, 536 (7615), pp. 165–170, 2016, ISSN: 1476-4687.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates, Parallelism and Divergence

Tempo and mode of genome evolution in a 50,000-generation experiment.

2015

Lenski R E; Wiser M J; Ribeck N; Blount Z D; Nahum J R; Morris J J; Zaman L; Turner C B; Wade B D; Maddamsetti R; Burmeister A R; Baird E J; Bundy J; Grant N A; Card K J; Rowles M; Weatherspoon K; Papoulis S E; Sullivan R; Clark C; Mulka J S; Hajela N

Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli Journal Article

Proceedings of the Royal Society B: Biological Sciences, 282 (1821), pp. 20152292, 2015, ISSN: 0962-8452.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Mutation Rates, Parallelism and Divergence

2014

Leiby N; Marx C J

Metabolic Erosion Primarily Through Mutation Accumulation, and Not Tradeoffs, Drives Limited Evolution of Substrate Specificity in Escherichia coli Journal Article

PLoS Biology, 12 (2), pp. e1001789, 2014, ISSN: 1545-7885.

Abstract | Links | BibTeX | Altmetric | Tags: Correlated Responses, Mutation Rates

2013

Wiser M J; Ribeck N; Lenski R E

Long-Term Dynamics of Adaptation in Asexual Populations Journal Article

Science, 342 (6164), pp. 1364–1367, 2013, ISSN: 0036-8075.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Mutation Rates, Theory and Simulations

Long-Term Dynamics of Adaptation in Asexual Populations

Wielgoss S; Barrick J E; Tenaillon O; Wiser M J; Dittmar W J; Cruveiller S; Chane-Woon-Ming B; Médigue C; Lenski R E; Schneider D

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load Journal Article

Proceedings of the National Academy of Sciences, 110 (1), pp. 222–227, 2013, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Genotypes and Phenotypes, Mutation Rates, Theory and Simulations

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

2012

Blount Z D; Barrick J E; Davidson C J; Lenski R E

Genomic analysis of a key innovation in an experimental Escherichia coli population Journal Article

Nature, 489 (7417), pp. 513–518, 2012, ISSN: 0028-0836.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Genome Evolution, Genotypes and Phenotypes, Historical Contingency, Mutation Rates

Genomic analysis of a key innovation in an experimental Escherichia coli population

2011

Wielgoss S; Barrick J E; Tenaillon O; Cruveiller S; Chane-Woon-Ming B; Médigue C; Lenski R E; Schneider D

Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli Journal Article

Genes|Genomes|Genetics, 1 (3), pp. 183-186, 2011, ISSN: 2160-1836.

Abstract | Links | BibTeX | Altmetric | Tags: Mutation Rates

2009

Barrick J E; Yu D S; Yoon S H; Jeong H; Oh T K; Schneider D; Lenski R E; Kim J F

Genome evolution and adaptation in a long-term experiment with Escherichia coli. Journal Article

Nature, 461 (7268), pp. 1243–7, 2009, ISSN: 1476-4687.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Genotypes and Phenotypes, Mutation Rates, Parallelism and Divergence

Genome evolution and adaptation in a long-term experiment with Escherichia coli.

Barrick J E; Lenski R E

Genome-wide Mutational Diversity in an Evolving Population of Escherichia coli Journal Article

Cold Spring Harbor Symposia on Quantitative Biology, 74 , pp. 119–129, 2009, ISSN: 0091-7451.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates

2003

Lenski R E; Winkworth C L; Riley M A

Rates of DNA Sequence Evolution in Experimental Populations of Escherichia coli During 20,000 Generations Journal Article

Journal of Molecular Evolution, 56 (4), pp. 498–508, 2003, ISSN: 0022-2844.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates

2000

Cooper V S; Lenski R E

The population genetics of ecological specialization in evolving Escherichia coli populations Journal Article

Nature, 407 (6805), pp. 736–739, 2000, ISSN: 0028-0836.

Abstract | Links | BibTeX | Altmetric | Tags: Correlated Responses, Fitness Trajectories, Mutation Rates

1999

Vulic M; Lenski R E; Radman M

Mutation, recombination, and incipient speciation of bacteria in the laboratory Journal Article

Proceedings of the National Academy of Sciences, 96 (13), pp. 7348–7351, 1999, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates

de Visser J A G M; Zeyl C W; Gerrish P J; Blanchard J L; Lenski R E

Diminishing returns from mutation supply rate in asexual populations. Journal Article

Science, 283 , pp. 404-406, 1999, ISSN: 00368075.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments, Fitness Trajectories, Mutation Rates

Papadopoulos D; Schneider D; Meier-Eiss J; Arber W; Lenski R E; Blot M

Genomic evolution during a 10,000-generation experiment with bacteria Journal Article

Proceedings of the National Academy of Sciences, 96 (7), pp. 3807–3812, 1999, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates

1997

Elena S F; Lenski R E

Long-term experimental evolution in Escherichia coli. VII. Mechanisms maintaining genetic variability within populations. Journal Article

Evolution, 51 (4), pp. 1058–1067, 1997, ISSN: 0014-3820.

Abstract | Links | BibTeX | Altmetric | Tags: Demography and Ecology, Fitness Trajectories, Mutation Rates, Theory and Simulations

21 entries « 1 of 2 »