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2021

Consuegra J; Gaffé J; Lenski R E; Hindré T; Barrick J E; Tenaillon O; Schneider D

Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria Journal Article

Nature Communications, 12 (1), pp. 980, 2021, ISSN: 2041-1723.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Mutation Rates

Deatherage D E; Barrick J E

High-throughput characterization of mutations in genes that drive clonal evolution using multiplex adaptome capture sequencing Journal Article

Cell Systems, 2021, ISSN: 24054712.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments, Fitness Trajectories, Methods and Miscellaneous

High-throughput characterization of mutations in genes that drive clonal evolution using multiplex adaptome capture sequencing

Card K J; Thomas M D; Graves J L; Barrick J E; Lenski R E

Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli Journal Article

Proceedings of the National Academy of Sciences, 118 (5), pp. e2016886118, 2021, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments, Genome Evolution, Historical Contingency

Gifford I; Dasgupta A; Barrick J E

Rates of gene conversions between Escherichia coli ribosomal operons Journal Article

G3: Genes, Genomes, Genetics, 11 (2), 2021, ISSN: 21601836.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments, Mutation Rates

2020

Blount Z D; Maddamsetti R; Grant N A; Ahmed S T; Jagdish T; Baxter J A; Sommerfeld B A; Tillman A; Moore J; Slonczewski J L; Barrick J E; Lenski R E

Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment Journal Article

eLife, 9 , pp. 1–64, 2020, ISSN: 2050-084X.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Demography and Ecology, Descendant Experiments, Genotypes and Phenotypes

Barrick J E; Deatherage D E; Lenski R E

A Test of the Repeatability of Measurements of Relative Fitness in the Long-Term Evolution Experiment with Escherichia coli Book Chapter

Banzhaf, Wolfgang; Cheng, Betty H C; Deb, Kalyanmoy; Holekamp, Kay E; Lenski, Richard E; Ofria, Charles; Pennock, Robert T; Punch, William F; Whittaker, Danielle J (Ed.): Evolution in Action: Past, Present and Future: A Festschrift in Honor of Erik D. Goodman, pp. 77–89, Springer International Publishing, Cham, 2020, ISBN: 978-3-030-39831-6.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories

2018

Leon D; D'Alton S; Quandt E M; Barrick J E

Innovation in an E. coli evolution experiment is contingent on maintaining adaptive potential until competition subsides Journal Article

PLOS Genetics, 14 (4), pp. e1007348, 2018, ISSN: 1553-7404.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Demography and Ecology, Historical Contingency

2017

Deatherage D E; Kepner J L; Bennett A F; Lenski R E; Barrick J E

Specificity of genome evolution in experimental populations of Escherichia coli evolved at different temperatures Journal Article

Proceedings of the National Academy of Sciences, 114 (10), pp. E1904–E1912, 2017, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Descendant Experiments

Good B H; McDonald M J; Barrick J E; Lenski R E; Desai M M

The dynamics of molecular evolution over 60,000 generations Journal Article

Nature, 551 (7678), pp. 45–50, 2017, ISSN: 14764687.

Abstract | Links | BibTeX | Altmetric | Tags: Demography and Ecology, Genome Evolution, Historical Contingency, Mutation Rates, Parallelism and Divergence

The dynamics of molecular evolution over 60,000 generations

2016

Tenaillon O; Barrick J E; Ribeck N; Deatherage D E; Blanchard J L; Dasgupta A; Wu G C; Wielgoss S; Cruveiller S; Medigue C; Schneider D; Lenski R E

Tempo and mode of genome evolution in a 50,000-generation experiment. Journal Article

Nature, 536 (7615), pp. 165–170, 2016, ISSN: 1476-4687.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution, Mutation Rates, Parallelism and Divergence

Tempo and mode of genome evolution in a 50,000-generation experiment.

2015

Maddamsetti R; Hatcher P J; Cruveiller S; Medigue C; Barrick J E; Lenski R E

Synonymous Genetic Variation in Natural Isolates of Escherichia coli Does Not Predict Where Synonymous Substitutions Occur in a Long-Term Experiment Journal Article

Molecular Biology and Evolution, 32 (11), 2015, ISSN: 0737-4038.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution

Quandt E M; Gollihar J; Blount Z D; Ellington A D; Georgiou G; Barrick J E

Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment. Journal Article

eLife, 4 (October), pp. e09696, 2015, ISSN: 2050-084X.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Genotypes and Phenotypes, Historical Contingency

Fine-tuning citrate synthase flux potentiates and refines metabolic innovation in the Lenski evolution experiment.

Maddamsetti R; Lenski R E; Barrick J E

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli Journal Article

Genetics, 200 (2), pp. 619-631, 2015, ISSN: 1943-2631.

Abstract | Links | BibTeX | Altmetric | Tags: Demography and Ecology, Fitness Trajectories, Genome Evolution

Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli

2014

Raeside C; Gaffé J; Deatherage D E; Tenaillon O; Briska A M; Ptashkin R N; Cruveiller S; Médigue C; Lenski R E; Barrick J E; Schneider D

Large Chromosomal Rearrangements during a Long-Term Evolution Experiment with Escherichia coli Journal Article

mBio, 5 (5), pp. 1–13, 2014, ISSN: 2161-2129.

Abstract | Links | BibTeX | Altmetric | Tags: Genome Evolution

Quandt E M; Deatherage D E; Ellington A D; Georgiou G; Barrick J E

Recursive genomewide recombination and sequencing reveals a key refinement step in the evolution of a metabolic innovation in Escherichia coli Journal Article

Proceedings of the National Academy of Sciences, 111 (6), pp. 2217–2222, 2014, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Genotypes and Phenotypes, Methods and Miscellaneous

2013

Barrick J E; Lenski R E

Genome dynamics during experimental evolution Journal Article

Nature Reviews Genetics, 14 (12), pp. 827–839, 2013, ISSN: 1471-0056.

Abstract | Links | BibTeX | Altmetric | Tags: Review Articles

Wielgoss S; Barrick J E; Tenaillon O; Wiser M J; Dittmar W J; Cruveiller S; Chane-Woon-Ming B; Médigue C; Lenski R E; Schneider D

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load Journal Article

Proceedings of the National Academy of Sciences, 110 (1), pp. 222–227, 2013, ISSN: 0027-8424.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Genotypes and Phenotypes, Mutation Rates, Theory and Simulations

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

2012

Blount Z D; Barrick J E; Davidson C J; Lenski R E

Genomic analysis of a key innovation in an experimental Escherichia coli population Journal Article

Nature, 489 (7417), pp. 513–518, 2012, ISSN: 0028-0836.

Abstract | Links | BibTeX | Altmetric | Tags: Citrate Evolution, Genome Evolution, Genotypes and Phenotypes, Historical Contingency, Mutation Rates

Genomic analysis of a key innovation in an experimental Escherichia coli population

2011

Wielgoss S; Barrick J E; Tenaillon O; Cruveiller S; Chane-Woon-Ming B; Médigue C; Lenski R E; Schneider D

Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli Journal Article

Genes|Genomes|Genetics, 1 (3), pp. 183-186, 2011, ISSN: 2160-1836.

Abstract | Links | BibTeX | Altmetric | Tags: Mutation Rates

Woods R J; Barrick J E; Cooper T F; Shrestha U; Kauth M R; Lenski R E

Second-Order Selection for Evolvability in a Large Escherichia coli Population Journal Article

Science, 331 (6023), pp. 1433–1436, 2011, ISSN: 0036-8075.

Abstract | Links | BibTeX | Altmetric | Tags: Fitness Trajectories, Genome Evolution, Historical Contingency

Second-Order Selection for Evolvability in a Large Escherichia coli Population
23 entries « 1 of 2 »